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Publications Roland Regoes

2011

Graw, F, Richter, K, Oxenius, A, Regoes, RR
Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011) XXX:XXX-XXX
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Rusert, P, Krarup, A, Magnus, C, Brandenberg, OF, Weber, J, Ehlert, AK, Regoes, RR, Guenthard, HF, Trkola, A
Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
JOURNAL OF EXPERIMENTAL MEDICINE (2011) 208:1419-1433
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Magnus, C, Regoes, RR
Restricted occupancy models for neutralization of HIV virions and populations
JOURNAL OF THEORETICAL BIOLOGY (2011) 283:192-202
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Alizon, S, Luciani, F, Regoes, RR
Epidemiological and clinical consequences of within-host evolution
TRENDS IN MICROBIOLOGY (2011) 19:24-32
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Johnson, PLF, Kochin, BF, McAfee, MS, Stromnes, IM, Regoes, RR, Ahmed, R, Blattman, JN, Antia, R
Vaccination Alters the Balance between Protective Immunity, Exhaustion, Escape, and Death in Chronic Infections
JOURNAL OF VIROLOGY (2011) 85:5565-5570
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Takizawa, H, Regoes, RR, Boddupalli, CS, Bonhoeffer, S, Manz, MG
Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation
JOURNAL OF EXPERIMENTAL MEDICINE (2011) 208:273-284
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zur Wiesch, PA, Kouyos, R, Engelstadter, J, Regoes, RR, Bonhoeffer, S
Population biological principles of drug-resistance evolution in infectious diseases
LANCET INFECTIOUS DISEASES (2011) 11:236-247
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Ruprecht, CR, Krarup, A, Reynell, L, Mann, AM, Brandenberg, OF, Berlinger, L, Abela, IA, Regoes, RR, Gunthard, HF, Rusert, P, Trkola, A
MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1
JOURNAL OF EXPERIMENTAL MEDICINE (2011) 208:439-454
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2010

Graw, F, Magnus, C, Regoes, RR
Theoretical analysis of the evolution of immune memory
BMC EVOLUTIONARY BIOLOGY (2010) 10:-
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Regoes, RR
Population genetics meets cancer genomics
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010) 107:18241-18242
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Kouyos, RD, Gordon, SN, Staprans, SI, Silvestri, G, Regoes, RR
Similar Impact of CD8+T Cell Responses on Early Virus Dynamics during SIV Infections of Rhesus Macaques and Sooty Mangabeys
PLOS COMPUTATIONAL BIOLOGY (2010) 6:-
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Magnus, C, Regoes, RR
Estimating the Stoichiometry of HIV Neutralization
PLOS COMPUTATIONAL BIOLOGY (2010) 6:e1000713-
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Ben-Ami, F, Ebert, D, Regoes, RR
Pathogen dose infectivity curves as a method to analyze the distribution of host susceptibility: a quantitative assessment of maternal effects after food stress and pathogen exposure
American Naturalist (2010) 175:106-115
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2009

Graw, F , Regoes, RR
Investigating CTL mediated killing with a 3D cellular automaton
PLOS COMPUTATIONAL BIOLOGY (2009) 5:e1000466-
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Magnus, C, Rusert, P, Bonhoeffer, S, Trkola, A, Regoes, RR
Estimating the Stoichiometry of Human Immunodeficiency Virus Entry
JOURNAL OF VIROLOGY (2009) 83:1523-1531
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2008

Ben-Ami, F, Regoes, RR, Ebert, D
A quantitative test of the relationship between parasite dose and infection probability across different host-parasite combinations
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2008) 275:853-859
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Salathe, M, Kouyos, RD, Regoes, RR, Bonhoeffer, S
Rapid parasite adaptation drives selection for high recombination rates
EVOLUTION (2008) 62:295-300
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Fouchet, D, Regoes, R
A Population Dynamics Analysis of the Interaction between Adaptive Regulatory T Cells and Antigen Presenting Cells
PLoS ONE (2008) 3:e2306-
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2007

Debarre, F, Bonhoeffer, S, Regoes, RR
The effect of population structure on the emergence of drug resistance during influenza pandemics
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2007) 4:893-906
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Regoes, RR, Yates, A, Antia, R
Mathematical models of cytotoxic T-lymphocyte killing
IMMUNOLOGY AND CELL BIOLOGY (2007) 85:274-279
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Regoes, RR, Barber, DL, Ahmed, R, Antia, R
Estimation of the rate of killing by cytotoxic T lymphocytes in vivo
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007) 104:1599-1603
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Mandl, JN, Regoes, RR, Garber, DA, Feinberg, MB
Estimating the effectiveness of simian immunodeficiency virus-specific CD8(+) T cells from the dynamics of viral immune escape
JOURNAL OF VIROLOGY (2007) 81:11982-11991
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2006

Bull, JJ, Regoes, RR
Pharmacodynarnics of non-replicating viruses, bacteriocins and lysins
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2006) 273:2703-2712
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Regoes, RR, Bonhoeffer, S
Emergence of drug-resistant influenza virus: Population dynamical considerations
SCIENCE (2006) 312:389-391
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Supplementary Material   Programs  

Regoes, RR, Bowen, EF, Cope, AV, Gor, D, Hassan-Walker, AF, Prentice, HG, Johnson, MA, Sweny, P, Burroughs, AK, Griffiths, PD, Bonhoeffer, S, Emery, VC
Modelling cytomegalovirus replication patterns in the human host: factors important for pathogenesis
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2006) 273:1961-1967
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Yates, A, Antia, R, Regoes, RR
How do pathogen evolution and host heterogeneity interact in disease emergence?
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2006) 273:3075-3083
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Handel, A, Regoes, RR, Antia, R
The role of compensatory mutations in the emergence of drug resistance
PLOS COMPUTATIONAL BIOLOGY (2006) 2:1262-1270
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2005

Regoes, RR, Bonhoeffer, S
The HIV coreceptor switch: a population dynamical perspective
TRENDS IN MICROBIOLOGY (2005) 13:269-277
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Supplementary Material   Programs  

Regoes, RR, Crotty, S, Antia, R, Tanaka, MM
Optimal replication of poliovirus within cells
AMERICAN NATURALIST (2005) 165:364-373
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Regoes, RR, Longini, IM, Feinberg, MB, Staprans, SI
Preclinical assessment of HIV vaccines and microbicides by repeated low-dose virus challenges
PLOS MEDICINE (2005) 2:798-807
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Programs  

Wiuff, C, Zappala, RM, Regoes, RR, Garner, KN, Baquero, F, Levin, BR
Phenotypic tolerance: Antibiotic enrichment of noninherited resistance in bacterial populations
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005) 49:1483-1494
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2004

Regoes, RR, Wiuff, C, Zappala, RM, Garner, KN, Baquero, F, Levin, BR
Pharmacodynamic functions: A multiparameter approach to the design of antibiotic treatment regimens
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004) 48:3670-3676
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Supplementary Material   Programs  

Regoes, RR, Antia, R, Garber, DA, Silvestri, G, Feinberg, MB, Staprans, SI
Roles of target cells and virus-specific cellular immunity in primary simian immunodeficiency virus infection
JOURNAL OF VIROLOGY (2004) 78:4866-4875
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2003

Regoes, RR, Hottinger, JW, Sygnarski, L, Ebert, D
The infection rate of Daphnia magna by Pasteuria ramosa conforms with the mass-action principle
EPIDEMIOLOGY AND INFECTION (2003) 131:957-966
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Antia, R, Regoes, RR, Koella, JC, Bergstrom, CT
The role of evolution in the emergence of infectious diseases
NATURE (2003) 426:658-661
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2002

Regoes, RR, Ebert, D, Bonhoeffer, S
Dose-dependent infection rates of parasites produce the Allee effect in epidemiology
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES (2002) 269:271-279
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Regoes, RR, Bonhoeffer, S
HIV coreceptor usage and drug treatment
JOURNAL OF THEORETICAL BIOLOGY (2002) 217:443-457
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Regoes, RR, Staprans, SI, Feinberg, MB, Bonhoeffer, S
Contribution of peaks of virus load to simian immunodeficiency virus pathogenesis
JOURNAL OF VIROLOGY (2002) 76:2573-2578
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2000

Regoes, RR, Nowak, MA, Bonhoeffer, S
Evolution of virulence in a heterogeneous host population
EVOLUTION (2000) 54:64-71
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1998

Regoes, RR, Wodarz, D, Nowak, MA
Virus dynamics: the effect of target cell limitation and immune responses on virus evolution
JOURNAL OF THEORETICAL BIOLOGY (1998) 191:451-462
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